Main Page
From QuB
QUB is software for Markov analysis of single-molecule kinetics, especially ion channel records.
With QuB's user-friendly graphical interfaces, you can
- simulate single-channel currents for any model
- calculate rate constants and voltage-dependence without fitting histograms
- detect current transitions in the presence of noise
- filter data, correct baseline, and select subintervals
- test all possible model topologies
- fit data to any function or system of ODEs
- (more...)
| Forum | Videos | Developers | Contact/bug reports |
See also
- Papers about QuB -- please cite the relevant paper
- Research using QuB -- and please send citations when you're published
- Macroscopic Analysis -- A tutorial
- Dynamic Clamp -- Modeling ion channels in real time
- How to satisfy cycle (im)balance
- How to import data
- QuB 2004 manual
- QuB 2008 manual
Outside Links
- @channelomics on twitter
- Other Software for ion channels
- ModelDB -- database of models for computational neuroscience
- Significance tests harm progress in forecasting (pdf)
- Linking Exponential Components to Kinetic States in Markov Models for Single-Channel Gating - Shelley and Magleby
- The Chloride Channel Song by Nathan Germick and Criss Hartzell
- Dr. Mark V. Shaney
Thanks
QuB is a public service provided by the State University of New York at Buffalo, located on scenic NYS Bicycle Route 517. QuB is funded by a grant from the National Institutes of Health. Please cite the relevant Papers about QuB in your research to ensure continued funding.
