Reasons to use QuB

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  • No need to program or understand Colquhoun and Hawkes
  • Solve for molecular rate constants instead of time constants
  • Solve the kinetics of multi-conductance channels
  • Solve for the concentration or voltage dependence of the rate constants
  • Try different models easily and compare them with an objective criterion, the likelihood
  • Analyze non-stationary data (where histograms don’t work)
  • Solve the kinetics of multi-channel patches
  • Check for stationarity in the data: do the rate constants vary with time?
  • Check if the kinetics are in equilibrium
  • Solve kinetics with hundreds, not millions, of events


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